Edwards will have to make some changes for this game with Emmanuel Agbadou and Tawanda Chirewa away with Ivory Coast and Zimbabwe at the Africa Cup of Nations while Yerson Mosquera is suspended.
Meanwhile, the Brentford game comes too soon for injured Hugo Bueno, which means there will be opportunities for young players.
On 18-year-old forward Mateus Mane who set up Tolu Arokodare's equaliser at Arsenal last Saturday: "He's brave, he's direct and he'll take risks. They're all things we want from forward players".
Despite the defeats, Edwards was pleased with the manner of his side's performances against title chasers Aston Villa and Arsenal: "It's a lot harder for me to sleep when we have a poor performance and we don't do things that we can control."
Edwards praised Hwang Hee-chan's tactical understanding: "Walking off the pitch at half-time at the Emirates, he's giving me the half-time talk. All of the things I've been talking about with the staff, he's seeing. He's really intelligent."
On Wolves' form at Molineux: "Our two best performances have come away from home. It hasn't got to be the world's best performance, but we have to show character, resilience and do the basics well."
On the role of home fans: "Supporters haven't seen the team win in such a long time. It's down to us. We've got to show some belief, some intensity. I know then that supporters will come with us."
On facing his former Wolves team-mate in Brentford boss Keith Andrews: "He was always going to be successful. It's not a shock - he's very intelligent. I'm looking forward to seeing Keith."
