Of course there have been communities left behind over the last 30-40 years (many areas of Wales would fit into that bracket) and giving the "establishment" a kicking is understandable in that context. Pick your $#@!ing battles though. Like I dunno, say, a General Election which we had a whole 13 months before this nonsense of a referendum.
Deprivation, unemployment, low wages, NHS issues etc in the UK have little or nothing to do with the EU. As will be borne out when none of that improves when we leave. Conflating the EU - which does of course need perpetual reform, like all long standing political entities - with penury which has been ideologically pushed by multiple, successive domestic Government policies (cross party, I hasten to add) is a political non-sequitur, it's like me stating that I'm going to stop eating pasta because I suffer from depression.
Not that these people who voted for change "just because" should be let off the hook completely, have a bloody look into what it is you're voting for. It isn't hard.