I'd keep podence and swap Hwang for guedes.
I don't think Nunes will start, moutinho might start depending on his fitness as he missed most of pre-season.
Semedo might start but could see him coming on as sub again.
Even if we don't get our strongest first XI due to fitness, the changes we're able to make now are decent ones.
Not for me, he's been poor so far this season and in a game where we are likely to be under pressure at times and need outlets, Podence is completely ineffective when he is receiving the ball nearer our goal.
Sa
Jonny Collins Kilman Ait Nouri
Donk Neves Nunes
MGW Guedes Neto
Is what I'd go for, dominate the midfield and target the space in behind their Wide CBs.